FreeFlow-Information Management Systems for Drug Discovery

Brief Description: A Drug Database and Analysis platform to aid in high-throughput drug screening, by providing researchers with a set of tools for storage, querying, analysis and visualization of raw data generated from laboratory instruments.

Participating Labs: UCSF DeRisi Lab, Biocomputing and Media Research Group

Research Purpose: The system is being developed under close collaboration with researchers at The Institute for Quantitative Biomedical Research to ensure the delivery of a highly effective and purposeful system to aid in biomedical research. We consider three key aspects of the information management problem, namely data processing, data modeling for storage and retrieval, and paradigms for user-data interaction. We have developed a prototype information management system for high-throughput screening, which is validated through its application in anti-malarial drug discovery. We aim to provide a publicly available website to share this database of anti-malarial drug compounds so other researchers in this field can benefit from the multitude of data captured by this system.

Collaboration Website: http://tintin.sfsu.edu/bin/view/Collaboration/FreeFlowGroup